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	Provedor de dados BABT (1) BJMBR (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Adham,Hamed (1) Al-Fayez,Musaed (1) Al-Rasheed,Nawal M. (1) Al-Rasheed,Nouf M. (1) Ali,Hanaa M. (1) Artigiani Neto,R. (1) Bagheri,Amir (1) Costa,P.P. da (1) Fadda,Laila (1) Ferrari,A.P. (1) Forones,N.M. (1) Hasan,Iman H. (1) Karimzadeh,Latifeh (1) Kouchesfehani,Homa Mohseni (1) Martins,F.P. (1) Mohamad,Raeesa A. (1) Nabiuni,Mohammad (1) Oshima,C.T. (1) Sheikholeslami,Azar (1) Mais... Palavra-chave Cyclooxygenase-2 (3) Acetaminophen (1) Barrett's esophagus (1) Ectopic gastric mucosa (1) Endoscopy (1) Gastric biopsies (1) Honeybee venom (1) Interlukin-6 (1) Polycystic ovarian syndrome (1) Thymoquinone (1) Vascular endothelial growth factor (1) Α-Lipoic acid (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2017 (1) 2013 (1) 2007 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Effect of bee venom on IL-6, COX-2 and VEGF levels in polycystic ovarian syndrome induced in Wistar rats by estradiol valerate J. Venom. Anim. Toxins incl. Trop. Dis. Karimzadeh,Latifeh; Nabiuni,Mohammad; Kouchesfehani,Homa Mohseni; Adham,Hamed; Bagheri,Amir; Sheikholeslami,Azar. Background : Polycystic ovarian syndrome (PCOS) is a low-grade inflammatory disease characterized by hyperandrogenemia, hirsutism, chronic anovulation and vascular disorder. Interleukin-6 (IL-6), cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) are triggered by inflammatory stimuli and lead to angiogenesis and pathogenesis of the ovary. Honeybee venom (HBV) contains an array of biologically active components possessing various pharmaceutical properties. This study was designed to assess the possibility of HBV application as an anti-inflammatory therapeutic agent to suppress levels of the main inflammatory mediators IL-6, COX-2 and VEGF. To induce PCOS, 1 mg of estradiol valerate (EV) per 100 g of body weight was subcutaneously (SC)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Polycystic ovarian syndrome; Honeybee venom; Interlukin-6; Cyclooxygenase-2; Vascular endothelial growth factor. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992013000100317 Hepatoprotective Role of α-Lipoic acid and Thymoquinone in Acetaminophen- Induced Liver Injury: Down-Regulation of COX-2 and flt-1 Expression BABT Al-Rasheed,Nawal M.; Fadda,Laila; Al-Rasheed,Nouf M.; Hasan,Iman H.; Ali,Hanaa M.; Al-Fayez,Musaed; Mohamad,Raeesa A.. ABSTRACT Acetaminophen (APAP) is a widely-used analgesic, while toxic doses of which induce liver injury. Inducible cyclooxygenase-2 (COX-2) is derived prostaglandins which play an anti-inflammatory role in acetaminophen-induced hepatotoxicity. Selective activation of vascular endothelial growth factor (VEGFR1, flt -1) on endothelial cells increased mRNA levels of hepatocyte mitogens (IL-6) and hepatocyte growth factor leading to prosurvival effects on hepatocytes. The aim of this study was to compare the hepatoprotective effect of N-acetylcysteine (NAC; the antidote for APAP) with that of α-Lipoic acid (ALA) and/or Thymoquinone (THQ) either alone or in combination on liver injury induced by APAP. APAP administration elevated most of the previously... Tipo: Info:eu-repo/semantics/article Palavras-chave: Acetaminophen; Α-Lipoic acid; Thymoquinone; Cyclooxygenase-2. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100427 Over-expression of cyclooxygenase-2 in endoscopic biopsies of ectopic gastric mucosa BJMBR Martins,F.P.; Artigiani Neto,R.; Oshima,C.T.; Costa,P.P. da; Forones,N.M.; Ferrari,A.P.. Ectopic gastric mucosa (EGM) is considered to be a congenital condition. Rare cases of adenocarcinoma have been described. There are no data justifying regular biopsies or follow-up. Cyclooxygenase-2 (COX-2) is a protein involved in gastrointestinal tumor development by inhibiting apoptosis and regulating angiogenesis. The aim of this prospective study was to evaluate COX-2 expression in EGM and compare it with normal tissue and Barrett's esophagus. We evaluated 1327 patients. Biopsies were taken from the inlet patch for histological evaluation and from the gastric antrum to assess Helicobacter pylori infection. Biopsies taken from normal esophageal, gastric antrum and body mucosa and Barrett's esophagus were retrieved from a tissue bank. EGM biopsies were... Tipo: Info:eu-repo/semantics/article Palavras-chave: Endoscopy; Ectopic gastric mucosa; Cyclooxygenase-2; Barrett's esophagus; Gastric biopsies. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001100005 Registros recuperados: 3 Primeira ... 1 ... Última

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